Ovarian Cancer Research Today is a free monthly online journal that collates and summarizes the latest research about Ovarian Cancer, including details on symptoms, causes, treatment, information.

Biomarkers of ovarian tumours.

Rapkiewicz AV, Espina V, Petricoin EF, Liotta LA

Laboratory of Pathology, National Cancer Institute/National Institutes of Health, Bethesda, MD 20892-1500, USA. rapkiewa@mail.nih.gov

Ovarian cancer is one of the most aggressive gynaecological malignancies and most often the high mortality is a direct result of delays in diagnosis. The development of an ovarian cancer-specific biomarker for the early detection of disease has the capacity to improve the dismal survival rate. Currently, there are multiple investigations that are utilising both genomic and proteomic technologies to identify genes, gene products and proteins that may potentially identify diagnostic ovarian cancer biomarkers. Here, we review the studies that are involved in biomarker development for the detection of ovarian cancer.

Published 15 November 2004 in Eur J Cancer, 40(17): 2604-12.
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